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Cat. No.
AKA-378
CAS No.
80994-59-8
MF
C9H12BNO4
MW
208.21
Borofalan can be used for Boron neutron capture research (BNCT). Borofalan can be used for the research of recurrent or locally advanced head and neck cancer.
Borofalan(10B)
10B-enriched L-4-BPA
80994-59-8
C9H12BNO4
208.21
98%-102%
Borofalan can be used for Boron neutron capture research (BNCT). Borofalan can be used for the research of recurrent or locally advanced head and neck cancer. Packing: 500g/bag,1kg/bag,5kg/bag Availability: In stock API Current Development Status: A3---Process Development / Scale-Up Reference: Aktin major API development processes: A1.Feasibility / Route Development A2.Laboratory Process Development A3.Process Development / Scale-Up A4.GMP Clinical Development A5.Commercial GMP Supply
[1].Coderre JA, Morris GM. The radiation biology of boron neutron capture therapy. Radiat Res. 1999;151(1):1-18.
[2].Barth RF, Soloway AH, Fairchild RG. Boron neutron capture therapy for cancer. Cancer Res. 1990;50(4):1061-1070.
[3].Barth RF, Vicente MG, Harling OK, et al. Current status of boron neutron capture therapy of cancer. Cancer Commun (Lond). 2018;38(1):35.
[4].Hirose K, Konno A, Hiratsuka J, et al. Boron neutron capture therapy using cyclotron-based epithermal neutron source and borofalan (^10B) for recurrent or locally advanced head and neck cancer (JHN002): An open-label phase II trial. Radiother Oncol. 2021;155:182-187.
[5].Ishiwata K. 4-Borono-2-[18F]-fluoro-L-phenylalanine PET for boron neutron capture therapy-oriented diagnosis. Ann Nucl Med. 2011;25(9):665-672.
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