AKA-378
Borofalan(10B)

Cat. No.

AKA-378

CAS No.

80994-59-8

MF

C9H12BNO4

MW

208.21

Borofalan can be used for Boron neutron capture research (BNCT). Borofalan can be used for the research of recurrent or locally advanced head and neck cancer.
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Technical Data
Description
Documents
Storage and Shipping
References
Product Name
Borofalan(10B)
Chemical name
10B-enriched L-4-BPA
CAS No.
80994-59-8
MF
C9H12BNO4
MW
208.21
Specifications
98%-102%
Description
Borofalan can be used for Boron neutron capture research (BNCT). Borofalan can be used for the research of recurrent or locally advanced head and neck cancer.
Packing: 500g/bag,1kg/bag,5kg/bag
Availability: In stock
API Current Development Status: A3---Process Development / Scale-Up
Reference: 
Aktin major API development processes:
A1.Feasibility / Route Development
A2.Laboratory Process Development
A3.Process Development / Scale-Up
A4.GMP Clinical Development
A5.Commercial GMP Supply
Documents
  • Specification sheet
For Certificate of Analysis (COA), Safety Data Sheet (SDS/MSDS) etc., please enquiry by email: info@aktin.com
Storage and Shipping
Avoid light. Store in a sealed container.
References

[1].Coderre JA, Morris GM. The radiation biology of boron neutron capture therapy. Radiat Res. 1999;151(1):1-18.

[2].Barth RF, Soloway AH, Fairchild RG. Boron neutron capture therapy for cancer. Cancer Res. 1990;50(4):1061-1070.

[3].Barth RF, Vicente MG, Harling OK, et al. Current status of boron neutron capture therapy of cancer. Cancer Commun (Lond). 2018;38(1):35.

[4].Hirose K, Konno A, Hiratsuka J, et al. Boron neutron capture therapy using cyclotron-based epithermal neutron source and borofalan (^10B) for recurrent or locally advanced head and neck cancer (JHN002): An open-label phase II trial. Radiother Oncol. 2021;155:182-187.

[5].Ishiwata K. 4-Borono-2-[18F]-fluoro-L-phenylalanine PET for boron neutron capture therapy-oriented diagnosis. Ann Nucl Med. 2011;25(9):665-672.

Disclaimer
The information provided on generic APIs is for general reference and market assessment purposes only. Regulatory status, market availability, specifications, patents, and commercial terms may vary by country and change over time. Users should independently verify all information with the relevant regulatory authorities and qualified professionals before making any regulatory, manufacturing, investment, or commercial decisions.
We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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